GXSC ADE chip successfully replaces ADS1296R
Time:2025-06-04
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In the medical field, portable defibrillators (ADE) are critical devices for saving patients‘ lives, and their reliability and stability are of paramount importance. Within the core circuitry of an ADE, the analog front-end (AFE) chip plays a critical role as the “signal hub,” directly influencing the diagnostic accuracy and therapeutic efficacy of the defibrillator through precise acquisition and processing of electrocardiogram (ECG) signals.
The bioelectric signal acquisition system of a portable defibrillator must meet three core requirements:
• Ultra-high precision (μV-level ECG signal detection)
• Strong anti-interference capability (signal recovery under 4000V high voltage during defibrillation)
• Ultra-low power consumption (ensuring long standby time in emergency situations)
Traditional solutions often use TI‘s ADS1296R, but GXSC‘s ADE series AFE chips, leveraging proprietary innovative technology, achieve comprehensive breakthroughs in performance, cost, and supply chain security, making them an ideal alternative choice.

The GXSC six-channel 24-bit physiological signal acquisition analog front-end GX1296R can precisely capture sleep-related bioelectric signals such as EEG, ECG, and EMG. It is 100% software and hardware compatible with the ADS1296R for sleep monitoring instrument solutions. This analog front-end chip is specifically designed for ECG applications and features functions such as respiration detection, right leg drive, lead disconnection detection, pacemaker detection, WCT, and can switch to internal clock and internal reference, thereby simplifying the ECG peripheral circuitry and significantly reducing the size, power consumption, and cost of the application product.
The GXSC GX1296R data rate can reach 15.625 SPS to 32 kSPS, enabling faster acquisition of ECG signals, meeting the real-time monitoring requirements for rapid changes in cardiac status. The input reference noise (average across all channels) is 4.11 μVpp (0.64 μVrms) (BW = 112.5 Hz, G = 6). Its excellent low-noise performance prevents self-noise from contaminating the original ECG signal, providing more accurate signal data and significantly improving diagnostic accuracy.
Key features of the GX1296R include:
• Data rate: 31.25 SPS to 32 kSPS
• Programmable gain: 1, 2, 3, 4, 6, 8, or 12
• Ultra-low input reference noise: 4.07 μVpp (0.64 μVrms) (BW = 150 Hz, G = 6)
• CMRR: 120 dB
• Flexible power consumption modes: High-Speed Mode (HS), Low-Power Mode (LP), Ultra-Low-Power Mode (ULP)
• In Low-Power Mode, power consumption is only 410 μW (AVDD = 3 V, DVDD = 1.8 V, ODR = 500 SPS, G = 6)
• Built-in low-temperature drift reference; built-in clock with adjustable frequency and external output capability
• Built-in right leg drive amplifier, lead disconnection detection, temperature sensor, test signal
• Supports digital pacing detection
• Adjustable data buffer depth (1/2/4/8/16/32)
• Offset/Gain error calibration function
• Power supply range: Analog power supply: 2.7V to 5.25V; Digital power supply: 1.8V to 5.25V
• Flexible power-off and standby modes
• SPI interface
• Operating temperature range: -40°C to +85°C





