ADS1299 Replacement: GX1299 Pin-Compatible 8-Channel 24-Bit EEG ADC
GX1299 is an eight-channel, low-noise analog front end developed for EEG, fetal ECG and multichannel biopotential acquisition. Its integrated architecture reduces the external components, board area and system power required by precision medical instruments.
The QFP-64 version provides direct pin-to-pin replacement for ADS1299, allowing existing designs to retain their schematic, PCB and processor software. An additional compact BGA-64 package is available for new space-constrained designs.
GX1299 as a Direct ADS1299 Replacement
GX1299 retains the eight-channel, 24-bit simultaneous-sampling delta-sigma architecture used by ADS1299. Each channel includes a programmable gain amplifier for acquiring low-level EEG and other biopotential signals.
Compatible analog inputs, reference and clock connections, patient-bias circuitry, control pins and SPI interface support direct migration from ADS1299. Existing MCU, DSP or FPGA data-acquisition logic can continue to be used.
GX1299 supports output data rates from 250 SPS to 64 kSPS, providing additional bandwidth for EEG, evoked-potential and other high-speed biopotential measurements.
Pin-to-Pin Hardware and Software Compatibility
The 10 mm × 10 mm QFP-64 version of GX1299 is designed for pin-to-pin hardware compatibility with ADS1299. Existing electrode-input networks, reference circuits, SRB connections, patient-bias output and SPI control signals can be retained.
GX1299 also supports software and interface compatibility with ADS1299 systems. Existing register configuration, channel-control procedures, interface timing and data-readout software can continue operating without modifying the processor interface.
For new compact products, GX1299 is also available in an 8 mm × 8 mm BGA-64 package. Both package versions operate from −40°C to +85°C.

GX1299 vs ADS1299: Key Specification Comparison
|
Specification |
ADS1299 |
GX1299 |
|
Resolution |
24-bit |
24-bit |
|
ADC Channels |
8 |
8 |
|
ADC Architecture |
Delta-Sigma |
Delta-Sigma |
|
Sampling Operation |
Eight-Channel Simultaneous Sampling |
Eight-Channel Simultaneous Sampling |
|
Output Data Rate |
250 SPS to 16 kSPS |
250 SPS to 64 kSPS |
|
Input Configuration |
Differential / Single-Ended |
Differential / Single-Ended |
|
Programmable Gain Amplifiers |
Integrated |
Integrated |
|
Internal Reference |
Integrated |
Integrated |
|
Internal Oscillator |
Integrated |
Integrated |
|
Patient-Bias Output |
Supported |
Supported |
|
SRB Referential Montage |
Supported |
Supported |
|
Lead-Off Detection |
Supported |
Supported |
|
Diagnostic Multiplexer |
Supported |
Supported |
|
Daisy-Chain Operation |
Supported |
Supported |
|
Integrated Data Buffer |
— |
Up to Eight Samples |
|
Digital Interface |
SPI |
SPI |
|
Package |
TQFP-64, 10 mm × 10 mm |
QFP-64, 10 mm × 10 mm / BGA-64, 8 mm × 8 mm |
|
Operating Temperature |
−40°C to +85°C |
−40°C to +85°C |
|
Pin-to-Pin Compatible |
— |
Yes, QFP-64 Version |
|
Schematic or PCB Changes Required |
— |
No |
|
Processor Interface Changes Required |
— |
No |
|
Software Modification Required |
— |
No |
GX1299 preserves the principal ADC architecture, channel count and EEG acquisition functions of ADS1299 while providing a higher maximum output data rate, integrated data buffering and an additional compact BGA package option.
Low-Noise Acquisition and System Monitoring
At 250 SPS and a gain of 24, GX1299 achieves input-referred noise of 1.28 µVpp or 0.23 µVrms over a 70 Hz bandwidth. At 64 kSPS, it provides a −3 dB bandwidth of 14.4 kHz for higher-frequency biopotential signals.
The input multiplexer supports offset testing, temperature monitoring, power-supply measurement and channel self-test. It can also select the common-mode level of any input channel to generate the patient-bias output signal.
Optional SRB connections route a common reference signal to multiple inputs for referential montage configurations. Integrated pull-up and pull-down resistors, excitation current sources and AC lead-off detection support electrode-connection monitoring.
Key GX1299 features include:
l Eight simultaneous-sampling 24-bit delta-sigma ADC channels
l Output data rates from 250 SPS to 64 kSPS
l Integrated low-noise programmable gain amplifiers
l Internal reference and oscillator
l Input-referred noise of 1.28 µVpp at 250 SPS
l 14.4 kHz bandwidth at 64 kSPS
l Patient-bias signal generation
l SRB referential montage support
l Lead-off detection and diagnostic functions
l SPI data interface
l Daisy-chain operation
l Integrated buffer for up to eight samples
l QFP-64 and BGA-64 package options
EEG and Biopotential Applications
GX1299 is suitable for:
l Electroencephalography equipment
l Fetal electrocardiography systems
l Sleep-study monitoring
l Bispectral index monitoring
l Evoked auditory potential measurement
l Multichannel biopotential acquisition
l Medical research instruments
l High-channel-count acquisition systems
Request the GX1299 Datasheet and Samples
GXSC provides GX1299 samples, datasheets, compatibility verification and technical support for ADS1299 replacement projects and new medical data-acquisition designs.
Contact GXSC for GX1299 samples, quotations, QFP-64 or BGA-64 package information and application support.





